| Identification |
| Name: | Benzoic acid,4-[[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbonyl]amino]- |
| Synonyms: | Am 580; CD336; NSC 608001; Ro 40-6055 |
| CAS: | 102121-60-8 |
| Molecular Formula: | C22H25 N O3 |
| Molecular Weight: | 351.48 |
| InChI: | InChI=1/C22H25NO3/c1-21(2)11-12-22(3,4)18-13-15(7-10-17(18)21)19(24)23-16-8-5-14(6-9-16)20(25)26/h5-10,13H,11-12H2,1-4H3,(H,23,24)(H,25,26) |
| Molecular Structure: |
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| Properties |
| Flash Point: | 232.6°C |
| Boiling Point: | 461°C at 760 mmHg |
| Density: | 1.154g/cm3 |
| Refractive index: | 1.593 |
| Biological Activity: | An analog of retinoic acid that acts as a selective RAR α agonist (EC 50 values are 0.3, 8.6 and 13 nM for RAR α , RAR β and RAR γ respectively). Significantly induces IL-4, IL-5 and IL-13 and inhibits IL-12 and IFN γ synthesis, and induces cell differentiation with over 7 times the activity of retinoic acid in vitro . |
| Flash Point: | 232.6°C |
| Storage Temperature: | −20°C |
| Safety Data |
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