| Identification |
| Name: | 1H-Purine-2,6-dione,8-cyclopentyl-3,9-dihydro-1,3-dipropyl- |
| Synonyms: | 1H-Purine-2,6-dione,8-cyclopentyl-3,7-dihydro-1,3-dipropyl- (9CI); 1,3-Dipropyl-8-cyclopentylxanthine;8-Cyclopentyl-1,3-dipropylxanthine; CPX; DPCPX; PD 116948 |
| CAS: | 102146-07-6 |
| Molecular Formula: | C16H24 N4 O2 |
| Molecular Weight: | 304.39 |
| InChI: | InChI=1/C16H24N4O2/c1-3-9-19-14-12(15(21)20(10-4-2)16(19)22)17-13(18-14)11-7-5-6-8-11/h11H,3-10H2,1-2H3,(H,17,18) |
| Molecular Structure: |
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| Properties |
| Flash Point: | 277.4°C |
| Boiling Point: | 535.1°Cat760mmHg |
| Density: | 1.195g/cm3 |
| Refractive index: | 1.564 |
| Biological Activity: | Potent and selective A 1 adenosine receptor antagonist, both in vitro and in vivo . K i values are 3.9, 130, 50 and 4000 nM for human A 1 , A 2A , A 2B and A 3 receptors respectively. |
| Flash Point: | 277.4°C |
| Color: | white |
| Usage: | DPCPX is a potent and very selective A1-adenosine receptor antagonist, with a Ki of 0.46 nM for A1 receptors in rat whole-brain membranes. Its 740-fold A1-selectivity is the highest reported for an adenosine antagonist |
| Safety Data |
| Hazard Symbols |
Xi: Irritant
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