Identification |
Name: | 1,3,5-Naphthalenetrisulfonicacid, 8,8'-[carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-, sodium salt(1:6) |
Synonyms: | 1,3,5-Naphthalenetrisulfonicacid, 8,8'-[carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-, hexasodium salt(9CI); NF 023 |
CAS: | 104869-31-0 |
Molecular Formula: | C35H26 N4 O21 S6 . 6 Na |
Molecular Weight: | 1106.86 |
Molecular Structure: |
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Properties |
Biological Activity: | A subtype-selective, competitive and reversible P2X 1 receptor antagonist. Displays IC 50 values of 0.21, 28.9, > 50 and > 100 μ M for human P2X 1 , P2X 3 , P2X 2 , and P2X 4 -mediated responses respectively. Selective over adrenoceptors, histamine and P2Y receptors. Also selectively inhibits the α -subunit of G o/i (EC 50 ~? 300 nM). |
Color: | white |
Safety Data |
Hazard Symbols |
Xi: Irritant
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