| Identification |
| Name: | Benzoic acid,2-[[3-(2-quinolinylmethoxy)phenyl]amino]- |
| Synonyms: | QMPB; SR2640 |
| CAS: | 105350-26-3 |
| Molecular Formula: | C23H18 N2 O3 |
| Molecular Weight: | 370.40062 |
| InChI: | InChI=1S/C23H18N2O3/c26-23(27)20-9-2-4-11-22(20)24-17-7-5-8-19(14-17)28-15-18-13-12-16-6-1-3-10-21(16)25-18/h1-14,24H,15H2,(H,26,27) |
| Molecular Structure: |
 |
| Properties |
| Flash Point: | 304.7 ºC |
| Boiling Point: | 580.3ºC |
| Density: | 1.322 g/cm3 |
| Refractive index: | 1.711 |
| Water Solubility: | DMSO: 50 mg/mL, soluble |
| Solubility: | DMSO: 50 mg/mL, soluble |
| Appearance: | yellow powder with a tan cast |
| Biological Activity: | Potent and selective competitive leukotriene D 4 and E 4 receptor antagonist. Inhibits LTD 4 - but not histamine-induced guinea pig ileum and trachea contraction (pA 2 = 8.7). Also inhibits LTD 4 -attenuation of human PMN chemotaxis. Orally active in vivo . |
| Flash Point: | 304.7 ºC |
| Storage Temperature: | 2-8°C |
| Color: | yellow, powder with a tan cast |
| Safety Data |
| Hazard Symbols |
Xi: Irritant
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