| Identification |
| Name: | 2H-Indol-2-one,1,3-dihydro-1-phenyl-3,3-bis(4-pyridinylmethyl)- |
| Synonyms: | DuP 996;Linopirdine |
| CAS: | 105431-72-9 |
| Molecular Formula: | C26H21 N3 O |
| Molecular Weight: | 391.4644 |
| InChI: | InChI=1/C26H21N3O/c30-25-26(18-20-10-14-27-15-11-20,19-21-12-16-28-17-13-21)23-8-4-5-9-24(23)29(25)22-6-2-1-3-7-22/h1-17H,18-19H2 |
| Molecular Structure: |
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| Properties |
| Flash Point: | 350.5 ºC |
| Boiling Point: | 655.9 ºC at 760 mmHg |
| Density: | 1.255 g/cm3 |
| Refractive index: | 1.669 |
| Biological Activity: | Blocker of KCNQ voltage-gated potassium channels; blocks KCNQ2+3/M-currents (IC 50 = 4-7 μ M) and KCNQ1 homomeric channels (IC 50 = 8.9 μ M). Augments hippocampal ACh release and is a cognitive enhancer following oral administration in vivo . |
| Flash Point: | 350.5 ºC |
| Safety Data |
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