| Identification | |
| Name: | Octadecanamide,N-[2-(3,4-dihydroxyphenyl)ethyl]- |
| Synonyms: | N-Stearoyldopamine |
| CAS: | 105955-10-0 |
| Molecular Formula: | C26H45 N O3 |
| Molecular Weight: | 419.6404 |
| Molecular Structure: |  |
| Properties | |
| Density: | 0.994 g/cm3 |
| Biological Activity: | Endogenous fatty acid dopamide that displays 'entourage' effects on endovanilloids NADA and anandamide. Inactive at TRPV1 and CB 1 receptors (at concentrations up to 5 μ M) and does not inhibit AMT or FAAH (IC 50 > 25 μ M). However, potentiates TRPV1-mediated effects of NADA in vitro and in vivo ; enhances effects on intracellular Ca 2+ (EC 50 lowered 3-fold) and nociception. Also inhibits arachidonate 5-lipoxygenase (IC 50 = 16 nM). |
| Safety Data | |
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