Spiro[1-azabicyclo[2.2.2]octane-3,5'-[1,3]oxathiolane],2'-methyl-, hydrochloride (1:1), (2'R,3R)-rel- (107220-28-0)

Identification
Name:	Spiro[1-azabicyclo[2.2.2]octane-3,5'-[1,3]oxathiolane],2'-methyl-, hydrochloride (1:1), (2'R,3R)-rel-
Synonyms:	Spiro[1-azabicyclo[2.2.2]octane-3,5'-[1,3]oxathiolane],2'-methyl-, hydrochloride, (2'R,3R)-rel- (9CI);Spiro[1-azabicyclo[2.2.2]octane-3,5'-[1,3]oxathiolane], 2'-methyl-,hydrochloride, cis-; AF 102B; Cevimeline hydrochloride; Evoxac; FKS 508; SND5008; SNI 2011; SNK 508; Saligren; cis-2-Methylspiro[1,3-oxathiolane-5,3'-quinuclidine]hydrochloride
CAS:	107220-28-0
Molecular Formula:	C10H17 N O S . Cl H
Molecular Weight:	235.774
InChI:	InChI=1/C10H17NOS.ClH/c1-8-12-10(7-13-8)6-11-4-2-9(10)3-5-11;/h8-9H,2-7H2,1H3;1H
Molecular Structure:
Properties
Flash Point:	140.4°C
Boiling Point:	308.5°Cat760mmHg
Density:	g/cm³
Solubility:	In water, 4.1X10+4 mg/L at 25 deg C /Estimated/
Biological Activity:	Selective M 1 receptor agonist. Induces atropine-sensitive contractions of isolated guinea pig ilea and trachea preparations (EC 50 values are 3.5 and 3 μ M respectively). Reverses AF64A-induced cognitive impairments in vivo .
Flash Point:	140.4°C
Safety Data