| Identification | |
| Name: | Eplerenone |
| CAS: | 107724-20-9 |
| Molecular Formula: | C24H30O6 |
| Molecular Weight: | 414.49 |
| InChI: | InChI=1/C24H30O6/c1-21-7-4-14(25)10-13(21)11-15(20(27)28-3)19-16-5-8-23(9-6-18(26)30-23)22(16,2)12-17-24(19,21)29-17/h10,15-17,19H,4-9,11-12H2,1-3H3/t15-,16+,17?,19?,21+,22+,23-,24-/m1/s1 |
| Molecular Structure: |  |
| Properties | |
| Melting Point: | 241-243oC |
| Density: | 1.31g/cm3 |
| Refractive index: | 1.587 |
| Solubility: | Very slightly soluble in water, with its solubility essentially pH dependent In water, 2.1X10-3 mg/L at 25 deg C (est) |
| Appearance: | White Solid |
| Specification: |
?Eplerenone (CAS NO.107724-20-9), its Synonyms are 9,11alpha-Epoxy-17-hydroxy-3-oxo-17alpha-pregn-4-ene-7alpha,21-dicarboxylic acid, gamma-lactone, methyl ester ; Epoxymexrenone ; Inspra ; Pregn-4-ene-7,21-dicarboxylic acid, 9,11-epoxy-17-hydroxy-3-oxo-, gamma-lactone, methyl ester, (7alpha,11alpha,17alpha)- . |
| Color: | White to off-white crystalline powder |
| Usage: | Selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoi |
| Safety Data | |
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