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9-Octadecenamide,N-(2-hydroxyethyl)-, (9Z)- (111-58-0)

Identification
Name:9-Octadecenamide,N-(2-hydroxyethyl)-, (9Z)-
Synonyms:9-Octadecenamide,N-(2-hydroxyethyl)-, (Z)-;Oleamide, N-(2-hydroxyethyl)- (6CI,7CI,8CI);AM3101;N-(2-Hydroxyethyl)oleamide;N-Oleoyl-2-aminoethanol;N-Oleoylethanolamine;Oleamide MEA;Oleic acid ethanolamide;Oleic acidmonoethanolamide;Oleoylethanolamide;
CAS:111-58-0
EINECS: 203-884-8
Molecular Formula: C20H39NO2
Molecular Weight: 325.52916
InChI: InChI=1S/C20H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h9-10,22H,2-8,11-19H2,1H3,(H,21,23)/b10-9-
Molecular Structure: (C20H39NO2) 9-Octadecenamide,N-(2-hydroxyethyl)-, (Z)-;Oleamide, N-(2-hydroxyethyl)- (6CI,7CI,8CI);AM3101;N-(2-H...
Properties
Melting Point: 50-60ºC
Density:0.915 g/cm3
Refractive index:1.473
Water Solubility:Soluble in DMSO (>25 mg/ml) and ethanol (>25 mg/ml)
Solubility:Soluble in DMSO (>25 mg/ml) and ethanol (>25 mg/ml)
Appearance:white to off-white solid
Specification:

 N-(2-Hydroxyethyl)-9-octadecenamide , its CAS NO. is 111-58-0, the synonyms are 9-Octadecenamide, N-(2-hydroxyethyl)- ; Monoethanolamine oleic acid amide ; N-(2-Hydroxyethyl)oleamide ; N-Oleoylethanolamine ; Oleamide MEA ; Oleoyl monoethanolamide .

Biological Activity: Lipid mediator and analog of anandamide (N-(2-Hydroxyethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide ) that is involved in peripheral regulation of feeding. Selective GPR55 agonist (EC 50 values are 0.44, >30 and >30 μ M at GPR55, CB 1 and CB 2 respectively) and PPAR α agonist (EC 50 = 120 nM). Induces satiety through activation of PPAR α and is also a ceramidase inhibitor. Also endogenous agonist at the GPR119 receptor.
Storage Temperature: −20°C
Safety Data
Hazard Symbols Xi:Irritant