| Identification | |
| Name: | Benzenesulfonic acid,4,4',4'',4'''-[carbonylbis[imino-5,1,3-benzenetriylbis(carbonylimino)]]tetrakis-,tetrasodium salt (9CI) |
| Synonyms: | NF 110 |
| CAS: | 111150-22-2 |
| Molecular Formula: | C41H32 N6 O17 S4 . 4 Na |
| Molecular Weight: | 0 |
| Molecular Structure: |  |
| Properties | |
| Biological Activity: | High affinity P2X 3 receptor antagonist (K i values are 36, 82 and 4144 nM for P2X 3 , P2X 1 and P2X 2 recombinant receptors respectively). Shows no activity at P2Y 1 , P2Y 2 and P2Y 11 receptors (IC 50 > 10 μ M). Potently inhibits α , β -meATP-evoked desensitizing currents in rat DRG neurons (IC 50 = 527 nM). Shows antitumor activity against several tumor types. |
| Safety Data | |
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