Identification |
Name: | 1H-Indol-5-ol,3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl]- |
Synonyms: | Roxindole |
CAS: | 112192-04-8 |
Molecular Formula: | C23H26 N2 O |
Molecular Weight: | 382.93 |
InChI: | InChI=1/C23H26N2O/c26-21-9-10-23-22(16-21)20(17-24-23)8-4-5-13-25-14-11-19(12-15-25)18-6-2-1-3-7-18/h1-3,6-7,9-11,16-17,24,26H,4-5,8,12-15H2 |
Molecular Structure: |
![(C23H26N2O) Roxindole](https://img1.guidechem.com/chem/e/dict/46/112192-04-8.jpg) |
Properties |
Flash Point: | 302°C |
Boiling Point: | 575.7°Cat760mmHg |
Density: | 1.173g/cm3 |
Refractive index: | 1.651 |
Biological Activity: | Dopamine D 2 autoreceptor agonist, with affinity for D 3 , D 4 and 5-HT 1 receptors (pK i values are 8.55, 8.93, 8.23, 9.42, 6.00 and 7.05 for human D 2 , D 3 , D 4 , 5-HT 1A , 5-HT 1B and 5-HT 1D receptors). Inhibits 5-HT uptake and is antidepressant in vivo . |
Flash Point: | 302°C |
Safety Data |
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