| Identification |
| Name: | Benzamide,4-(acetylamino)-N-(2-aminophenyl)- |
| Synonyms: | Acetyldinaline;PD 123654;Tacedinaline;CI 994;Goe 5549; |
| CAS: | 112522-64-2 |
| Molecular Formula: | C15H14N2O2 |
| Molecular Weight: | 269.2985 |
| InChI: | InChI=1/C15H15N3O2/c1-10(19)17-12-8-6-11(7-9-12)15(20)18-14-5-3-2-4-13(14)16/h2-9H,16H2,1H3,(H,17,19)(H,18,20) |
| Molecular Structure: |
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| Properties |
| Density: | 1.322 g/cm3 |
| Refractive index: | 1.707 |
| Appearance: | white |
| Biological Activity: | Orally active histone deacetylase (HDAC) inhibitor (K i values are 0.41, 0.75, >100 and >100 μ M for HDAC1, HDAC3, HDAC6 and HDAC8 respectively). Mediates G 1 cell cycle arrest, inhibits proliferation and induces apoptosis in vitro and in vivo . |
| Safety Data |
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