| Identification | |
| Name: | Morphinan-6-one,7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-, (9a,13a,14a)- |
| Synonyms: | 7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-9-alpha,13-alpha,14-alpha-morphinan-6-one;BRN 0095280;CCRIS 1550;Coculine;Cucoline;Kukoline;Sabianine A;Sinomenine; |
| CAS: | 115-53-7 |
| EINECS: | 204-094-6 |
| Molecular Formula: | C19H23NO4 |
| Molecular Weight: | 329.38 |
| InChI: | InChI=1/C19H23NO4/c1-20-7-6-19-10-14(21)16(24-3)9-12(19)13(20)8-11-4-5-15(23-2)18(22)17(11)19/h4-5,9,12-13,22H,6-8,10H2,1-3H3/t12-,13+,19-/m1/s1 |
| Molecular Structure: |  |
| Properties | |
| Transport: | 1544 |
| Density: | 1.3 g/cm3 |
| Refractive index: | |
| Solubility: | Insoluble |
| Appearance: | White powder |
| Specification: | Safety Statements:53-22-26-36/37/39-45 53:Avoid exposure - obtain special instruction before use 22:Do not breathe dust 26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 36/37/39:Wear suitable protective clothing, gloves and eye/face protection 45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) |
| Packinggroup: | III |
| Biological Activity: | Natural anti-inflammatory morphinan analog. Causes degranulation of mast cells in mammalian tissues to release histamine and suppresses production of proinflammatory cytokines. Also displays antinociceptive activity, possibly through activation of the μ -opioid receptor. Stimulates short-term renewal of human embryonic stem cells (ESCs) in vitro . |
| Storage Temperature: | Keep tightly closed. Store in a cool dry place. |
| Usage: | Anti-inflammatory. |
| Safety Data | |
| Hazard Symbols |
T: Toxic
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