| Identification |
| Name: | 1H-1,2,4-Triazole,1-[(1Z)-2-chloro-2-(2,4-dichlorophenyl)ethenyl]- |
| Synonyms: | 1H-1,2,4-Triazole,1-[2-chloro-2-(2,4-dichlorophenyl)ethenyl]-, (Z)-; Loreclezole; R 72063 |
| CAS: | 117857-45-1 |
| Molecular Formula: | C10H6 Cl3 N3 |
| Molecular Weight: | 0 |
| InChI: | InChI=1/C10H6Cl3N3/c11-7-1-2-8(9(12)3-7)10(13)4-16-6-14-5-15-16/h1-6H/b10-4- |
| Molecular Structure: |
![(C10H6Cl3N3) 1H-1,2,4-Triazole,1-[2-chloro-2-(2,4-dichlorophenyl)ethenyl]-, (Z)-; Loreclezole; R 72063](https://img1.guidechem.com/chem/e/dict/28/117857-45-1.jpg) |
| Properties |
| Flash Point: | 207°C |
| Boiling Point: | 418.7°Cat760mmHg |
| Density: | 1.48g/cm3 |
| Refractive index: | 1.65 |
| Biological Activity: | Subtype-selective GABA A receptor modulator. Acts as a positive allosteric modulator of β 2 or β 3-subunit containing receptors. Also acts as a negative modulator at a novel regulatory site, enhancing GABA A receptor sensitization. Inhibits homomeric ρ 1 GABA C receptors. |
| Flash Point: | 207°C |
| Safety Data |
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