| Identification |
| Name: | Benzoic acid, 2-[(5a)-4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-ylidene]hydrazide |
| Synonyms: | Benzoicacid, [(5a)-4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-ylidene]hydrazide(9CI); Naloxone benzoylhydrazone |
| CAS: | 119630-94-3 |
| Molecular Formula: | C26H27 N3 O4 |
| Molecular Weight: | 445.51 |
| InChI: | InChI=1/C26H27N3O4/c1-2-13-29-14-12-25-21-17-8-9-19(30)22(21)33-23(25)18(10-11-26(25,32)20(29)15-17)27-28-24(31)16-6-4-3-5-7-16/h2-9,20,23,30,32H,1,10-15H2,(H,28,31)/b27-18+/t20-,23-,25?,26?/m1/s1 |
| Molecular Structure: |
![(C26H27N3O4) Benzoicacid, [(5a)-4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-ylidene]hydrazide(9CI); Nalox...](https://img1.guidechem.com/chem/e/dict/34/119630-94-3.jpg) |
| Properties |
| Flash Point: | °C |
| Boiling Point: | °Cat760mmHg |
| Density: | 1.44g/cm3 |
| Refractive index: | 1.722 |
| Biological Activity: | Mixed opioid receptor agonist/antagonist. Acts as a potent and full agonist at κ , and a partial agonist at μ and δ opioid receptors (pEC 50 values are 9.45, 8.74 and 8.61 in a cAMP assay, 9.70, 8.59 and 8.49 in a [ 35 S]GTP γ S binding assay respectively). Fails to exert agonist effects at NOP receptors and antagonizes agonist-induced NOP activation. Stimulates κ -, μ - and δ -mediated analgesia and blocks NOP-induced supraspinal nociception. |
| Flash Point: | °C |
| Storage Temperature: | −20°C |
| Color: | yellow |
| Safety Data |
| |
 |
