| Identification |
| Name: | 1H-Indole-1-carboxamide,5-chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-, (3Z)- |
| Synonyms: | 1H-Indole-1-carboxamide,5-chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-, (Z)-; CP 66248;Tenidap |
| CAS: | 120210-48-2 |
| Molecular Formula: | C14H9 Cl N2 O3 S |
| Molecular Weight: | 320.75 |
| InChI: | InChI=1/C14H9ClN2O3S/c15-7-3-4-9-8(6-7)11(13(19)17(9)14(16)20)12(18)10-2-1-5-21-10/h1-6,19H,(H2,16,20) |
| Molecular Structure: |
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| Properties |
| Flash Point: | 270.7°C |
| Boiling Point: | 523.9°Cat760mmHg |
| Density: | 1.58g/cm3 |
| Refractive index: | 1.756 |
| Biological Activity: | NSAID that preferentially inhibits COX-1 (IC 50 values are < 0.03, 1.2 and > 30 μ M for COX-1, COX-2 and 5-lipoxygenase respectively). Inhibits formation of pro-inflammatory arachidonic acid metabolites in isolated human peripheral polymorphonuclear leukocytes. Opener of inward rectifying hK IR 2.3 channel (EC 50 = 402 nM). |
| Flash Point: | 270.7°C |
| Safety Data |
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