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Amprolium (121-25-5)

Identification
Name:Amprolium
Synonyms:Amprolsol;Amprovine;Anticoccid;1-[(4-Amino-2-propyl-5-pyrimidinyl)methyl]-2-picoliniumchloride (6CI);2-Picolinium, 1-[(4-amino-2-propyl-5-pyrimidinyl)methyl]-,chloride (8CI);Pyridinium,1-[(4-amino-2-propyl-5-pyrimidinyl)methyl]-2-methyl-, chloride (9CI);Ampisol;Amprolium chloride;Amprolium plus;
CAS:121-25-5
EINECS: 204-458-4
Molecular Formula: C14H19ClN4
Molecular Weight: 278.78046
InChI: InChI=1S/C14H19N4.ClH/c1-3-6-13-16-9-12(14(15)17-13)10-18-8-5-4-7-11(18)2;/h4-5,7-9H,3,6,10H2,1-2H3,(H2,15,16,17);1H/q+1;/p-1
Molecular Structure: (C14H19ClN4) Amprolsol;Amprovine;Anticoccid;1-[(4-Amino-2-propyl-5-pyrimidinyl)methyl]-2-picoliniumchloride (6CI)...
Properties
Density:g/cm3
Stability:Stable. Incompatible with strong acids, strong bases, strong oxidizing agents.
Water Solubility:Stability Stable. Incompatible with strong acids, strong bases,strong oxidizing agents. Toxicology Believed to be of low toxicity. Toxicity data (The meaning of
Solubility:Stability Stable. Incompatible with strong acids, strong bases,strong oxidizing agents. Toxicology Believed to be of low toxicity. Toxicity data (The meaning of
Appearance:solid
Specification:

Mode of action: thiamine analog, competitively inhibits the active transport of thiamine.? The coccidia are 50 times as sensitive to this inhibition as is the host.
Pharmacokinetics: Freely soluble in water.
Dose:
In dogs and cats:? "extra label use":? 300 to 400 mg/kg, SID for 5 days or 110 to 220 mg/kg SID for 7 to 12 days.
In chickens:?? For prevention of coccidiosis:? 36.3 - 113.5 g/ton in the feed or in the drinking water at 0.012%.? No withdrawal is needed.

Safety Data
 

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