| Identification | |
| Name: | Benzeneethanamine,3,4-dimethoxy-N-methyl-N-[3-[4-[[1-methyl-3-(1-methylethyl)-1H-indol-2-yl]sulfonyl]phenoxy]propyl]- |
| Synonyms: | SR33805 |
| CAS: | 121346-32-5 |
| Molecular Formula: | C32H40 N2 O5 S |
| Molecular Weight: | 654.77 |
| InChI: | InChI=1/C31H38N2O5S.C3H4O4/c1-22(2)30-26-9-6-7-10-27(26)32-31(30)39(34,35)25-14-12-24(13-15-25)38-20-8-18-33(3)19-17-23-11-16-28(36-4)29(21-23)37-5;4-2(5)1-3(6)7/h6-7,9-16,21-22,32H,8,17-20H2,1-5H3;1H2,(H,4,5)(H,6,7) |
| Molecular Structure: |  |
| Properties | |
| Flash Point: | 394.5°C |
| Boiling Point: | 728.7°C at 760 mmHg |
| Biological Activity: | Potent Ca 2+ channel antagonist; binds allosterically to the a 1 -subunit of L-type Ca 2+ channels (K d = 20 pM), at a site distinct from other types of blocker. Shows some selectivity for vascular smooth muscle, inducing vasorelaxation without producing inotropic or chronotropic effects. Inhibits PDGF-stimulated smooth muscle cell proliferation. |
| Flash Point: | 394.5°C |
| Safety Data | |
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