| Identification | |
| Name: | Phenol,3,3',3'',3'''-(7,8-dihydro-21H,23H-porphine-5,10,15,20-tetrayl)tetrakis- |
| Synonyms: | 3,3',3'',3'''-(7,8-Dihydroporphyrin-5,10,15,20-tetrayl)tetraphenol;5,10,15,20-Tetra(m-hydroxyphenyl)chlorin;5,10,15,20-Tetrakis(m-hydroxyphenyl)chlorin;8-Dihydroporphyrin-5;EF 9;Foscan;Fosgel;Foslip;Fospeg;mTHPC; |
| CAS: | 122341-38-2 |
| Molecular Formula: | C44H32N4O4 |
| Molecular Weight: | 680.75 |
| InChI: | InChI=1/C44H32N4O4/c49-29-9-1-5-25(21-29)41-33-13-15-35(45-33)42(26-6-2-10-30(50)22-26)37-17-19-39(47-37)44(28-8-4-12-32(52)24-28)40-20-18-38(48-40)43(36-16-14-34(41)46-36)27-7-3-11-31(51)23-27/h1-17,19,21-24,46-47,49-52H,18,20H2/b41-33-,41-34-,42-35-,42-37-,43-36-,43-38-,44-39-,44-40- |
| Molecular Structure: |  |
| Properties | |
| Density: | 1.386 g/cm3 |
| Refractive index: | 1.734 |
| Specification: |
The IUPAC name of?Temoporfin is?3-[10,15,20-tris(3-hydroxyphenyl)-2,3,22,24-tetrahydroporphyrin-5-yl]phenol . With the CAS registry number 122341-38-2, it is also named?as?3,3',3'',3'''-(7,8-Dihydroporphyrin-5,10,15,20-tetrayl)tetraphenol ; 3,3',3',3'''-(7,8-Dihydroporphyrin-5,10,15,20-tetrayl)tetraphenol ; EF9 ; Foscan ; Phenol, 3,3',3',3'''-(7,8-dihydro-21H,23H-porphine-5,10,15,20-tetrayl)tetrakis- ; UNII-FU21S769PF ; meso-Tetrahydroxyphenylchlorin?. The product's?classification code are antineoplastic,?antineoplastic agents,?dermatologic agents,?photosensitizing agents and?radiation-sensitizing agents. The brand name?of temoporfin is?Foscan which?marketed in the European Union. It is a photosensitizer used in chemotherapy for the treatment of squamous cell carcinoma of the head and neck.?In a murine tumor model,?the?distribution of temoporfin?can be used as?a new photosensitizer for the photodynamic therapy of cancer. |
| Usage: | Bone Cancer Therapy, Head and Neck Cancer Therapy, Oncolytic Drugs, Pancreatic Cancer Therapy, Photodynamic Therapy, Prostate Cancer Therapy |
| Safety Data | |
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