| InChI: | InChI=1/C10H11ClFN5O3/c11-10-15-7(13)5-8(16-10)17(2-14-5)9-4(12)6(19)3(1-18)20-9/h2-4,6,9,18-19H,1H2,(H2,13,15,16)/t3-,4+,6-,9-/m1/s1 |
| Specification: |
Side effects
1.Side effects on tumor lysis syndrome (TLS): TLS is very serious and can lead to death if it is not treated right away.?
Clofarabine can?quickly kills leukaemia cells in the blood. Then the body may react to this. Symptoms include fast breathing, fast heartbeat, low blood pressure, and fluid in the lungs.
2.Side effects on Bone marrow problems (suppression). Clofarabine can stop the bone marrow from making enough red blood cells, white blood cells, and platelets. Serious side effects that can happen because of bone marrow suppression include severe infection (sepsis), bleeding, and anemia.
3.Effects on pregnancy and breastfeeding. Girls and women should not become pregnant or breastfeed during treatment which harm the baby.
4.Effects on Dehydration and low blood pressure.?Clofarabine (CAS NO.123318-82-1) can cause vomiting and diarrhea which may lead to low body fluid (dehydration). Signs and symptoms of dehydration include dizziness, lightheadedness, fainting spells, or decreased urination.
5.Other side effects. The most common side effects are stomach problems (including vomiting, diarrhea, and nausea), and effects on blood cells (including low red blood cells count, low white blood cell count, low platelet count, fever, and infection. Clofarabine can also cause tachycardia and can affect the liver and kidneys.
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