Benzamide,N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-, hydrochloride (1:1) (123464-89-1)

Identification
Name:	Benzamide,N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-, hydrochloride (1:1)
Synonyms:	Benzamide,N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-, monohydrochloride (9CI);Benzamide, N-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-, monohydrochloride, (R)-;PNU 282987
CAS:	123464-89-1
Molecular Formula:	C14H17 Cl N2 O . Cl H
Molecular Weight:	264.75058
InChI:	InChI=1/C14H17ClN2O/c15-12-3-1-11(2-4-12)14(18)16-13-9-17-7-5-10(13)6-8-17/h1-4,10,13H,5-9H2,(H,16,18)/t13-/m0/s1
Molecular Structure:
Properties
Flash Point:	214.8°C
Boiling Point:	431.5°Cat760mmHg
Density:	1.27g/cm³
Refractive index:	1.612
Biological Activity:	Highly selective α 7 nAChR agonist (K i = 26 nM) displaying negligible blockade of α 1 β 1 γ δ and α 3 β 4 nAChRs (IC 50 ≥ 60 μ M). Found to be inactive against a panel of 32 receptors at 1 μ M, except 5-HT 3 receptors (K i = 930 nM).
Flash Point:	214.8°C
Safety Data