| Identification |
| Name: | Methanesulfonamide,N-[2-(cyclohexyloxy)-4-nitrophenyl]- |
| Synonyms: | N-(2-Cyclohexyloxy-4-nitrophenyl)methanesulfonamide;NS 398; Taisho NS 398 |
| CAS: | 123653-11-2 |
| Molecular Formula: | C13H18 N2 O5 S |
| Molecular Weight: | 314.36 |
| InChI: | InChI=1/C13H18N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h7-9,11,14H,2-6H2,1H3 |
| Molecular Structure: |
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| Properties |
| Flash Point: | 250.5°C |
| Boiling Point: | 490.6°Cat760mmHg |
| Density: | 1.377g/cm3 |
| Refractive index: | 1.592 |
| Biological Activity: | Selective cyclooxygenase-2 inhibitor (IC 50 values are 3.8 and > 100 μ M for COX-2 and COX-1 respectively). Induces apoptosis in colorectal tumor cells and elevates COX-2 protein expression in vitro . Orally active and non-ulcerogenic analgesic and anti-inflammatory in vivo . |
| Flash Point: | 250.5°C |
| Color: | off-white |
| Safety Data |
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