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Losartan potassium (124750-99-8)

Identification
Name:Losartan potassium
Synonyms:Lotim;L-158086;Ocsaar;Losacor;Tenopres;Lortaan;Losaprex;Hyzaar;Niten;DuP 753;Losartan monopotassium salt;MK 954;Lorzaan;Cozaar;Llosartan;Losartanpotassium;Lorzaar;1H-Imidazole-5-methanol,2-butyl-4-chloro- 1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]- methyl]-,monopotassium salt;2-Butyl-4-chloro-1-(2-(tetrazol-5-yl)biphenyl-4-ylmethyl)-1H-imidazole-5-methanol potassium;MK-0954;Losacar;MK 0954;potassium [2-butyl-5-chloro-3-[[4-[2-(2,3,4-triaza-1-azanidacyclopenta-2,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol;Cozaar (TN);
CAS:124750-99-8
Molecular Formula: C22H22ClKN6OK
Molecular Weight: 461.01
InChI: InChI=1/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12,30H,2-3,8,13-14H2,1H3;/q-1;+1
Molecular Structure: (C22H22ClKN6OK) Lotim;L-158086;Ocsaar;Losacor;Tenopres;Lortaan;Losaprex;Hyzaar;Niten;DuP 753;Losartan monopotassium ...
Properties
Melting Point: 183.5-184.5 deg C /Losartan/
Solubility:Freely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone.
Appearance:white to off-white crystalline powder
Specification:

?Losartan potassium (CAS NO.124750-99-8) is also named as 1H-Imidazole-5-methanol, 2-butyl-4-chloro-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-, monopotassium salt ; 2-Butyl-4-chloro-1-(2'-(tetrazol-5-yl)biphenyl-4-ylmethyl)-
1H-imidazole-5-methanol potassium ; 2-Butyl-4-chloro-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)imidazole-5-methanol, monopotassium salt ; Cozaar ; Du Pont 753 ; DuP 753 ; HSDB 7043 ; L-158086 ; Lifezar ; Lortaan ; Lorzaan ; Lorzaar ; Losacar ; Losacor ; Losaprex ; Losartan ;?Lotim ; MK 0954 ; MK-0954 ; Neo Lotan ; Niten ; Ocsaar ; Tenopres ; UNII-3ST302B24A?.?Losartan potassium (CAS NO.124750-99-8)?is?white to off-white crystalline powder.

Biological Activity: Selective non-peptide angiotensin AT 1 receptor antagonist. Inhibits the contractile effects of angiotensin II on rabbit aorta and jugular vein (pA 2 = 8.27). Orally active antihypertensive agent.
Color: A white to off-white free-flowing crystalline powder.
Light yellow solid /Losartan/
Usage:

 Losartan potassium (CAS NO.124750-99-8) can be used as a nonpeptide angiotensin II AT1-receptor antagonist.

Safety Data
Hazard Symbols Xi: Irritant