| Specification: |
The Miramistin with the cas number 126338-77-0. It is also called benzyl-dimethyl-[3-(tetradecanoylamino)propyl]azanium chloride, which is also it's IUPAC name, and it's system Names is N-benzyl-N,N-dimethyl-3-(tetradecanoylamino)propan-1-aminium chloride.
Physical properties about Miramistin are: (1)ACD/LogP: 2.76 # of Rule of 5 Violations: 0 ; (2)ACD/LogD (pH 5.5): 2.76 ACD/LogD (pH 7.4): 2.76 ; (3)ACD/BCF (pH 5.5): 73.9 ACD/BCF (pH 7.4): 73.9 ; (4)ACD/KOC (pH 5.5): 757.14 ACD/KOC (pH 7.4): 757.14 ; (5)#H bond acceptors: 3 #H bond donors: 1 ; (6)#Freely Rotating Bonds: 18 Polar Surface Area: 20.31 Å2
Uses of Miramistin: Miramistin belongs to antiseptic group cationic detergents which can increase permeability of cell membranes of microorganisms, resulting in cytolysis. It is active against gram such as Staphylococcus streptococci and Bacillus anthracis. Besides, it is also against gram including Escherichia coli, salmonella, shigella, vibriony, gonokokki and so on. In addition, it still has good effects on spirohet, agents diphtheria, Chlamydia, viruses (simple herpes, influenza, HIV) and some mushrooms (ith trihofiton and red). It is usually applied to treat with trauma such as heal wounds, burns, bullet, inflammatory diseases of the female genitalia, genital candidiasis uretritov, prostatitov, syphilis, gonorrhea, trichomoniasis, chlamydia, stomatitov, peridontitis, disease LOR- bodies (otites, chronic sinusitis, tonsillitis, laringity) and also fungal lesions.
Specific treatment method:
(1) At Burns, or the wound surface (with the band) placed towel, soaked 0.01% solution.
(2) When watering bullet solution, and wound tamponiruyut svischevye moves swabs, soaked solution.
(3) In Urethritis appoint 2-3 ml of the urethra 2-3 times a day during the week.
(4) To treat inflammatory diseases of female genital daily impose intravaginalno tampons, soaked solution, or use electrophoresis for 10-14 days.
(5) In introducing otites designate 1-2 ml of external audible passage, with patients and laryngitis-rinse 4-6 times a day, with washed-nasal sinus.
(6) In combination treatment for peritonitis washed abdominal cavity 5-6 l of solution.
You can still convert the following datas into molecular structure :
(1).SMILES:[Cl-].O=C(NCCC[N+](C)(Cc1ccccc1)C)CCCCCCCCCCCCC
(2).InChI=1/C26H46N2O.ClH/c1-4-5-6-7-8-9-10-11-12-13-17-21-26(29)27-22-18-23-28(2,3)24-25-19-15-14-16-20-25;/h14-16,19-20H,4-13,17-18,21-24H2,1-3H3;1H
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