Butanoic acid,4-[[3-[(1E)-2-(4-cyclobutyl-2-thiazolyl)ethenyl]phenyl]amino]-2,2-diethyl-4-oxo- (128312-51-6)

Identification
Name:	Butanoic acid,4-[[3-[(1E)-2-(4-cyclobutyl-2-thiazolyl)ethenyl]phenyl]amino]-2,2-diethyl-4-oxo-
Synonyms:	Butanoicacid, 4-[[3-[2-(4-cyclobutyl-2-thiazolyl)ethenyl]phenyl]amino]-2,2-diethyl-4-oxo-,(E)-;(E)-4-[[3-[2-(4-Cyclobutyl-2-thiazolyl)ethenyl]phenyl]amino]-2,2-diethyl-4-oxobutanoicacid; 3'-[(E)-2-(4-Cyclobutyl-2-thiazolyl)vinyl]2,2-diethylsuccinanilic acid;Cinalukast; Ro 24-5913
CAS:	128312-51-6
Molecular Formula:	C23H28 N2 O3 S
Molecular Weight:	412.545
InChI:	InChI=1/C23H28N2O3S/c1-3-23(4-2,22(27)28)14-20(26)24-18-10-5-7-16(13-18)11-12-21-25-19(15-29-21)17-8-6-9-17/h5,7,10-13,15,17H,3-4,6,8-9,14H2,1-2H3,(H,24,26)(H,27,28)/b12-11+
Molecular Structure:
Properties
Flash Point:	°C
Boiling Point:	°Cat760mmHg
Density:	1.258g/cm³
Refractive index:	1.655
Biological Activity:	Potent, selective CysLT 1 (LTD 4 ) leukotriene receptor antagonist (IC 50 = 6.4 nM). Inhibits LTD 4 -induced bronchoconstriction in guinea pigs when administered intravenously, orally or by aerosol.
Flash Point:	°C
Storage Temperature:	2-8°C
Color:	off-white
Usage:	A novel leukotriene D4 antagonist
Safety Data