Nitrosourea (CAS NO.13010-20-3) compounds are DNA alkylating agents and are often used in chemotherapy. Nitrosourea (CAS NO.13010-20-3) compounds are lipophilic and thus can cross the blood-brain barrier, making them useful in the treatment of brain tumors such as glioblastoma multiforme
Some Nitrosoureas (e.g. Lomustine) have been associated with the development of interstitial lung disease.
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