| Identification |
| Name: | S(-)-WIN 55 212-3 MESYLATE |
| Synonyms: | [(3S)-2,3-DIHYDRO-5-METHYL-3-(4-MORPHOLINYLMETHYL)PYRROLO[1,2,3-DE]-1,4-BENZOXAZIN-6-YL]-1-NAPHTHALENYL-METHANONE MONOMETHANESULFONATE;WIN 55,212-3 MESYLATE;S(-)-[2,3-Dihydro-5-methyl-3-[(4-morpholinyl)methyl]pyrrolo[1,2,3-de]-1,4-benzoxazinyl]-(1-naphthalenyl)methanone mesylate salt;S(-)-WIN 55,212-3 mesylate salt |
| CAS: | 131543-25-4 |
| Molecular Formula: | C28H30N2O6S |
| Molecular Weight: | 522.6126 |
| InChI: | InChI=1/C27H26N2O3.CH4O3S/c1-18-25(27(30)22-9-4-7-19-6-2-3-8-21(19)22)23-10-5-11-24-26(23)29(18)20(17-32-24)16-28-12-14-31-15-13-28;1-5(2,3)4/h2-11,20H,12-17H2,1H3;1H3,(H,2,3,4)/t20-;/m0./s1 |
| Molecular Structure: |
![(C28H30N2O6S) [(3S)-2,3-DIHYDRO-5-METHYL-3-(4-MORPHOLINYLMETHYL)PYRROLO[1,2,3-DE]-1,4-BENZOXAZIN-6-YL]-1-NAPHTHALE...](https://img.guidechem.com/structure/131543-25-4.gif) |
| Properties |
| Flash Point: | 333.4°C |
| Boiling Point: | 627.7°C at 760 mmHg |
| Appearance: | off-white solid |
| Biological Activity: | Novel, low potency CB 2 receptor silent antagonist and CB 1 receptor partial inverse agonist. Competitively antagonizes effects of CP 55,940 (pA 2 = 6.1) and SR 144528 (pEC 50 = 5.3) at CB 2 receptors and acts as a partial inverse agonist at CB 1 receptors (pIC 50 = 5.5). Displays modest activity at human melatonin MT 1 and muscarinic M 4 receptors, but is selective over several other GPCRs. |
| Flash Point: | 333.4°C |
| Color: | off-white |
| Safety Data |
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