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Propanedinitrile,2-[2-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazinylidene]- (131741-08-7)

Identification
Name:Propanedinitrile,2-[2-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazinylidene]-
Synonyms:Propanedinitrile,[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazono]- (9CI);((4-(1,4,5,6-Tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrazono)propanedinitrile;2-[[4-(4-Methyl-6-oxo-4,5-dihydro-1H-pyridazin-3-yl)phenyl]hydrazinylidene]propanedinitrile;
CAS:131741-08-7
Molecular Formula: C14H12N6O
Molecular Weight: 280.28
InChI: InChI=1/C14H12N6O/c1-9-6-13(21)19-20-14(9)10-2-4-11(5-3-10)17-18-12(7-15)8-16/h2-5,9,17H,6H2,1H3,(H,19,21)/t9-/m0/s1
Molecular Structure: (C14H12N6O) Propanedinitrile,[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazono]- (9CI);((4-(...
Properties
Density:1.336g/cm3
Refractive index:1.673
Specification:

   The chemical synonyms of 2-[[4-(4-Methyl-6-oxo-4,5-dihydro-1h-pyridazin-3-yl)phenyl]hydrazinylidene]propanedinitrile (131741-08-7) are 2-[[4-(4-Methyl-6-oxo-4,5-dihydro-1h-pyridazin-3-yl)phenyl]hydrazinylidene]propanedinitrile ; ((4-(1,4,5,6-Tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrazono)propanedinitrile ; Simendan ; Simendan R--[4-(1,4,5,6-Tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl] hydrozono]-propanedinitrile ; R-(-)-4-(1,4,5,6-Tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl hydrozono-propanedinitrile .The product of  2-[[4-(4-Methyl-6-oxo-4,5-dihydro-1h-pyridazin-3-yl)phenyl]hydrazinylidene]propanedinitrile (131741-08-7)  has  well tolerated, with other cardiovascular drugs such as β blockers, ACE inhibitors, calcium antagonists, nitrates, digoxin, warfarin, aspirin, etc. in conjunction with, the more secure . Abroad have been carried out in several large clinical trials, adverse reactions are mild and rarely serious arrhythmia.

Safety Data
 

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