2-Azetidinone,3-hydroxy-4-phenyl-, (3R,4S)- (132127-34-5)

The (3R,4S)-3-Hydroxy-4-phenyl-2-azetidinone ,its cas register number is 132127-34-5.It also can be called as (3R-cis)-3-Hydroxy-4-phenyl-2-azetidinone and the Systematic name about this chemicals is (3R,4S)-3-hydroxy-4-phenylazetidin-2-one .It belongs to the following product categories, such as Chiral Reagents, Chiral chemicals, Intermediates, Intermediates & Fine Chemicals and Pharmaceuticals .

This chemicals is a white solid and it can be used as docetaxel or paclitaxel intermediate.The(3R,4S)-3-hydroxy-4-phenyl-2-azetidinone react with chloro-triethyl-silane can be got 4-phenyl-3-triethylsilanyloxy-azetidin-2-one .And also it react with 2-methoxy-propene can get 3-(1-methoxy-1-methyl-ethoxy)-4-phenyl-azetidin-2-one .

Following are the chemical properties about (3R,4S)-3-Hydroxy-4-phenyl-2-azetidinone :(1)#H bond acceptors: 3 ; (2)#H bond donors: 2 ; (3)#Freely Rotating Bonds: 2 ; (4)Polar Surface Area: 49.33Å ; (5)Index of Refraction: 1.612 ; (6)Molar Refractivity: 43.348 cm³ ; (7)Molar Volume: 124.679 cm³ ; (8)Surface Tension: 55.743 dyne/cm ; (9)Enthalpy of Vaporization: 72.298 kJ/mol ; (10)Vapour Pressure: 0 mmHg at 25°C .

This chemicals can be described computed from structure:
(1)SMILES: O=C2N[C@@H](c1ccccc1)[C@H]2O
(2)InChI: InChI=1/C9H9NO2/c11-8-7(10-9(8)12)6-4-2-1-3-5-6/h1-5,7-8,11H,(H,10,12)/t7-,8+/m0/s1
(3)InChIKey: FBZSDKXFQUKDLD-JGVFFNPUBT