Identification |
Name: | 3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester,hydrochloride (1:1) |
Synonyms: | 3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester,monohydrochloride (9CI);Cardiovasc;Carmen;Corifeo;Lercadip;Lercan;Lercapin;Lercaton;Lerkamen;Lerzam;R 75;Rec15/2375;Renovia;Vasodip;Zandip;Zanicor; |
CAS: | 132866-11-6 |
Molecular Formula: | C36H42ClN3O6 |
Molecular Weight: | 648.19 |
InChI: | InChI=1S/C36H41N3O6.ClH/c1-24-31(34(40)44-6)33(28-18-13-19-29(22-28)39(42)43)32(25(2)37-24)35(41)45-36(3,4)23-38(5)21-20-30(26-14-9-7-10-15-26)27-16-11-8-12-17-27;/h7-19,22,30,33,37H,20-21,23H2,1-6H3;1H |
Molecular Structure: |
 |
Properties |
Transport: | UN 2811 |
Density: | g/cm3 |
Appearance: | Pale-Yellow Powder |
Specification: |
?3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester,hydrochloride (1:1) , its cas register number 132866-11-6. It also can be called?Lercanidipine hydrochloride ; and?1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester hydrochloride ;?Cardiovasc ; Carmen ; Corifeo ; Lercadip ; Lercan ; Lercanidipine HCl ; Lercanidipine hydrochloride ; Lercapin ; Lercaton ; Lerkamen ; Lerzam ; Vasodip ; Zandip ; and Zanicor .?Its classification code are?Antihypertensive compound and Calcium channel blockers.
|
Biological Activity: | L-type Ca 2+ channel blocker that displays higher vascular selectivity than Felodipine (4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester ). Causes peripheral vasodilation with only weak negative inotropic activity. Antihypertensive. |
Usage: | 3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester,hydrochloride (1:1) (CAS NO.132866-11-6) can be used as a dihydropyridine calcium channel blocker. |
Safety Data |
Hazard Symbols |
T: Toxic
|
|
 |