| Identification |
| Name: | 2(1H)-Pyrimidinone,5-[3-[(1S,2S,4R)-bicyclo[2.2.1]hept-2-yloxy]-4-methoxyphenyl]tetrahydro- |
| Synonyms: | Tetrahydro-5-(4-methoxy-3-((1S,2S,4R)-2-norbomyloxy)phenyl)-2(1H)-pyrimidinone; |
| CAS: | 135637-46-6 |
| Molecular Formula: | C18H24N2O3 |
| Molecular Weight: | 0 |
| InChI: | InChI=1/C18H24N2O3/c1-22-15-5-4-12(14-9-19-18(21)20-10-14)8-17(15)23-16-7-11-2-3-13(16)6-11/h4-5,8,11,13-14,16H,2-3,6-7,9-10H2,1H3,(H2,19,20,21)/t11-,13+,16+/m1/s1 |
| Molecular Structure: |
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| Properties |
| Flash Point: | 282.2°C |
| Boiling Point: | 543°Cat760mmHg |
| Density: | 1.178g/cm3 |
| Refractive index: | 1.56 |
| Biological Activity: | Selective inhibitor of phosphodiesterase type 4 (IC 50 values are 1.9, > 100, > 100, > 100 and > 100 μ M for human lung PDE4, lung PDE1, lung PDE2, heart PDE3 and platelet PDE-V respectively) that displays no significant PDE4 isozyme selectivity. Inhibits hydrolysis of cAMP in isolated human peripheral blood monocytes, eosinophils and T cells.? Displays anti-inflammatory and bronchodilatory effects in vivo . |
| Flash Point: | 282.2°C |
| Safety Data |
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