Benzamide,4-fluoro-N-[2-[4-(7-methoxy-1-naphthalenyl)-1-piperazinyl]ethyl]-,hydrochloride (1:?) (135721-98-1)

Identification
Name:	Benzamide,4-fluoro-N-[2-[4-(7-methoxy-1-naphthalenyl)-1-piperazinyl]ethyl]-,hydrochloride (1:?)
Synonyms:	Benzamide,4-fluoro-N-[2-[4-(7-methoxy-1-naphthalenyl)-1-piperazinyl]ethyl]-,hydrochloride (9CI); S 14506
CAS:	135721-98-1
Molecular Formula:	C24H26 F N3 O2 . x Cl H
Molecular Weight:	443.94
InChI:	InChI=1/C24H26FN3O2.ClH/c1-30-21-10-7-18-3-2-4-23(22(18)17-21)28-15-13-27(14-16-28)12-11-26-24(29)19-5-8-20(25)9-6-19;/h2-10,17H,11-16H2,1H3,(H,26,29);1H
Molecular Structure:
Properties
Flash Point:	328.3°C
Boiling Point:	619.2°Cat760mmHg
Density:	g/cm³
Biological Activity:	Highly potent selective 5-HT 1A receptor full agonist (pK i values are 9.0, 6.6, 7.5, 6.6 and < 6.0 for 5-HT 1A , 5-HT 1B , 5-HT 1C , 5-HT 2 and 5-HT 3 receptors respectively). Possibly binds between the agonist binding site and the G protein interaction switch site, affecting the activation mechanism, and may display positive cooperativity. Anxiolytic following central administration in vivo .
Flash Point:	328.3°C
Safety Data