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Benzenesulfonamide,N-[2-[[[3-(4-chlorophenyl)-2-propen-1-yl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxy- (139298-40-1)

Identification
Name:Benzenesulfonamide,N-[2-[[[3-(4-chlorophenyl)-2-propen-1-yl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxy-
Synonyms:Benzenesulfonamide,N-[2-[[[3-(4-chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxy-(9CI); KN 93
CAS:139298-40-1
Molecular Formula: C26H29 Cl N2 O4 S
Molecular Weight: 501.03746
InChI: InChI=1S/C26H29ClN2O4S/c1-28(17-5-6-21-9-11-23(27)12-10-21)20-22-7-3-4-8-26(22)29(18-19-30)34(31,32)25-15-13-24(33-2)14-16-25/h3-16,30H,17-20H2,1-2H3/b6-5+
Molecular Structure: (C26H29ClN2O4S) Benzenesulfonamide,N-[2-[[[3-(4-chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-N-(2-hydroxyethy...
Properties
Density:1.288 g/cm3
Refractive index:1.626
Water Solubility:Soluble to 100 mM in DMSO
Solubility:Soluble to 100 mM in DMSO
Appearance:White Solid
Biological Activity: Potent inhibitor of CaM kinase II (IC 50 = 0.37 μ M). Also a direct extracellular open channel blocker of voltage-gated potassium channels (IC 50 = 307 nM for Kv1.5); independent of CaM kinase II inhibition.
Storage Temperature: 2-8°C
Color: white
Safety Data
 

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