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1(2H)-Pyrimidinepropanoicacid, a-amino-5-fluoro-3,4-dihydro-2,4-dioxo-,(aS)- (140187-23-1)

Identification
Name:1(2H)-Pyrimidinepropanoicacid, a-amino-5-fluoro-3,4-dihydro-2,4-dioxo-,(aS)-
Synonyms:1(2H)-Pyrimidinepropanoicacid, a-amino-5-fluoro-3,4-dihydro-2,4-dioxo-,(S)-; (5S)-Fluorowillardiine; (S)-5-Fluorowillardiine
CAS:140187-23-1
Molecular Formula: C7H8 F N3 O4
Molecular Weight: 217.154523
InChI: InChI=1S/C7H8FN3O4/c8-3-1-11(2-4(9)6(13)14)7(15)10-5(3)12/h1,4H,2,9H2,(H,13,14)(H,10,12,15)/t4-/m0/s1
Molecular Structure: (C7H8FN3O4) 1(2H)-Pyrimidinepropanoicacid, a-amino-5-fluoro-3,4-dihydro-2,4-dioxo-,(S)-; (5S)-Fluorowillardiine;...
Properties
Melting Point: 235ºC
Flash Point: °C
Boiling Point: °Cat760mmHg
Density:1.64 g/cm3
Refractive index:1.601
Water Solubility:Soluble to 50 mM in 1 eq. NaOH.
Solubility:Soluble to 50 mM in 1 eq. NaOH.
Appearance:off-white Solid
Biological Activity: A more potent and selective AMPA receptor agonist (at hGluR1 and hGluR2) than AMPA itself (K i = 14.7, 25.1, and 1820 nM for hGluR1, hGluR2 and hGluR5 respectively). Also available as part of the AMPA Receptor Tocriset™ .
Flash Point: °C
Safety Data