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3-Pyrrolidineaceticacid, 2-carboxy-4-[(1Z,3E,5R)-5-carboxy-1-methyl-1,3-hexadien-1-yl]-,(2S,3S,4S)- (14277-97-5)

Identification
Name:3-Pyrrolidineaceticacid, 2-carboxy-4-[(1Z,3E,5R)-5-carboxy-1-methyl-1,3-hexadien-1-yl]-,(2S,3S,4S)-
Synonyms:3-Pyrrolidineaceticacid, 2-carboxy-4-(5-carboxy-1-methyl-1,3-hexadienyl)-, [2S-[2a,3b,4b(1Z,3E,5S*)]]-; 3-Pyrrolidineacetic acid,2-carboxy-4-[(1Z,3E,5R)-5-carboxy-1-methyl-1,3-hexadienyl]-, (2S,3S,4S)- (9CI);Domoic acid (6CI,7CI); (-)-Domoic acid; L-Domoic acid; NSC 288031
CAS:14277-97-5
Molecular Formula: C15H21 N O6
Molecular Weight: 311.33034
InChI: InChI=1S/C15H21NO6/c1-8(4-3-5-9(2)14(19)20)11-7-16-13(15(21)22)10(11)6-12(17)18/h3-5,9-11,13,16H,6-7H2,1-2H3,(H,17,18)(H,19,20)(H,21,22)/b5-3+,8-4-/t9-,10+,11-,13+/m1/s1
Molecular Structure: (C15H21NO6) 3-Pyrrolidineaceticacid, 2-carboxy-4-(5-carboxy-1-methyl-1,3-hexadienyl)-, [2S-[2a,3b,4b(1Z,3E,5S*)]...
Properties
Melting Point: 228ºC
Density:1.273 g/cm3
Refractive index:1.544
Appearance:White to off-white solid.
Specification:

 L-Domoic acid ,its cas register number is 14277-97-5. It also can be called DA ; [2S-[2a,3b,4b(1Z,3E,5S*)]]-2-Carboxy-4-(5-carboxy-1-methyl-1,3-hexadienyl)-3-pyrrolidineacetic Acid ; Domoate and Domoic acid .It is an amino acid associated with certain harmful algal blooms and is the neurotoxin which causes amnesic shellfish poisoning (ASP).
 L-Domoic acid (CAS NO.14277-97-5) is a structural analog of kainic acid and proline. And it can bioaccumulate in marine organisms such as anchovies, shellfish, and sardines that feed on the phytoplankton known to produce this toxin. It can accumulate in high concentrations in the tissues of these plankton feeders when the toxic phytoplankton itself is high in concentration in the surrounding waters.

Biological Activity: More potent and possibly more selective than kainate at kainate receptors, as demonstrated in electrophysiological studies.
Storage Temperature: −20°C
Color: white
Safety Data
Hazard Symbols Xn: Harmful
 

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