| Identification | |
| Name: | Candesartan cilexetil |
| Synonyms: | 1H-Benzimidazolium, 7-carboxy-1-(2-((cyclohexylcarbonyl)oxy)ethyl)-2-ethoxy-1-(2-(1H-tetrazol-5-yl)(1,1-biphenyl)-4-yl)-, hydroxide, inner salt, (+-)-;TCV-116;Atacand;Atacand (TN);1-cyclohexyloxycarbonyloxyethyl 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzoimidazole-4-carboxylate;TCV 116;Candesartancilexetil; |
| CAS: | 145040-37-5 |
| Molecular Formula: | C33H34N6O6 |
| Molecular Weight: | 610.67 |
| InChI: | InChI=1/C33H34N6O6/c1-3-42-32-34-28-15-9-14-27(31(40)43-21(2)44-33(41)45-24-10-5-4-6-11-24)29(28)39(32)20-22-16-18-23(19-17-22)25-12-7-8-13-26(25)30-35-37-38-36-30/h7-9,12-19,21,24H,3-6,10-11,20H2,1-2H3,(H,35,36,37,38) |
| Molecular Structure: |  |
| Properties | |
| Flash Point: | 463.8 oC |
| Boiling Point: | 843.3 oC at 760 mmHg |
| Density: | 1.37 g/cm3 |
| Refractive index: | 1.665 |
| Appearance: | White crystalline powder |
| Specification: |
? Candesartan cilexetil (CAS NO.145040-37-5), its Synonyms are (+-)-1-Hydroxyethyl 2-ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxylate, cyclohexyl carbonate (ester) ; Atacand ; 1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-, 1-(((cyclohexyloxy)carbonyl)oxy)ethyl ester, ( -)- ; 1H-Benzimidazolium, 7-carboxy-1-(2-cyclohexylcarbonyl)oxy)ethyl)-2-ethoxy-1-(2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)-, hydroxide, inner salt, (+-)- . |
| Flash Point: | 463.8 oC |
| Usage: | Ester prodrug; hydrolized in vivo to the active carboxylic acid. Used in treatment of congestive heart failure. Antihypertensive |
| Safety Data | |
| Hazard Symbols |
Xn: Harmful
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