Identification |
Name: | Urea,N-[(3R)-2,3-dihydro-1-[2-(2-methylphenyl)-2-oxoethyl]-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-N'-(3-methylphenyl)- |
Synonyms: | Urea,N-[2,3-dihydro-1-[2-(2-methylphenyl)-2-oxoethyl]-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-N'-(3-methylphenyl)-,(R)-; 1H-1,4-Benzodiazepine, urea deriv.; YM 022 |
CAS: | 145084-28-2 |
Molecular Formula: | C32H28 N4 O3 |
Molecular Weight: | 516.59 |
InChI: | InChI=1/C32H28N4O3/c1-21-11-10-15-24(19-21)33-32(39)35-30-31(38)36(20-28(37)25-16-7-6-12-22(25)2)27-18-9-8-17-26(27)29(34-30)23-13-4-3-5-14-23/h3-19,30H,20H2,1-2H3,(H2,33,35,39)/t30-/m0/s1 |
Molecular Structure: |
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Properties |
Flash Point: | 398.6°C |
Boiling Point: | 735.4°Cat760mmHg |
Density: | 1.23g/cm3 |
Refractive index: | 1.647 |
Biological Activity: | Extremely potent and highly selective non-peptide CCK 2 silent antagonist (K i values are 68 pM and 63 nM at CCK 2 and CCK 1 receptors respectively). Acts in vivo to potently inhibit gastrin-induced gastric acid secretion and histidine decarboxylase activation with a long duration of action. |
Flash Point: | 398.6°C |
Safety Data |
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