| Identification |
| Name: | 1H-Isoindole-1,3(2H)-dione,5,6-bis[(4-fluorophenyl)amino]- |
| Synonyms: | CGP 53353 |
| CAS: | 145915-60-2 |
| Molecular Formula: | C20H13 F2 N3 O2 |
| Molecular Weight: | 365.33 |
| InChI: | InChI=1/C20H13F2N3O2/c21-11-1-5-13(6-2-11)23-17-9-15-16(20(27)25-19(15)26)10-18(17)24-14-7-3-12(22)4-8-14/h1-10,23-24H,(H,25,26,27) |
| Molecular Structure: |
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| Properties |
| Flash Point: | °C |
| Boiling Point: | °Cat760mmHg |
| Density: | 1.472g/cm3 |
| Refractive index: | 1.702 |
| Biological Activity: | Selective inhibitor of PKC β II (IC 50 values are 0.41 and 3.8 μ M for PKC β II and PKC β I respectively). Also inhibits prionogenic Sup35 fibrillization (IC 50 ~ 3.4 μ M) and inhibits de novo A β 42 assembly in vitro . |
| Flash Point: | °C |
| Storage Temperature: | 2-8°C |
| Safety Data |
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