Piperidine,3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenyl-, (2S,3S)- (148700-85-0)

Identification
Name:	Piperidine,3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenyl-, (2S,3S)-
Synonyms:	Piperidine,3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenyl-, (2S-cis)-; (+)-L 733060;(+)-L-733060;(2S,3S)-2-Phenyl-3-[[3,5-bis(trifluoromethyl)benzyl]oxy]piperidine; L 733060
CAS:	148700-85-0
Molecular Formula:	C20H19 F6 N O
Molecular Weight:	439.82
InChI:	InChI=1/C20H19F6NO.ClH/c21-19(22,23)15-9-13(10-16(11-15)20(24,25)26)12-28-17-7-4-8-27-18(17)14-5-2-1-3-6-14;/h1-3,5-6,9-11,17-18,27H,4,7-8,12H2;1H/t17-,18-;/m0./s1
Molecular Structure:
Properties
Flash Point:	185.7°C
Boiling Point:	383.5°C at 760 mmHg
Biological Activity:	A potent antagonist of human tachykinin NK 1 receptors (K i values are 0.08, 0.2 and 93.13 nM for gerbil, human and rat receptors respectively). Produces anxiolytic-like effects in the gerbil elevated plus-maze; orally bioavailable and brain penetrant.
Flash Point:	185.7°C
Storage Temperature:	2-8°C
Color:	white
Safety Data