| Identification |
| Name: | Benzeneethanamine,4-methoxy-3-(2-phenylethoxy)-N,N-dipropyl-, hydrochloride (1:1) |
| Synonyms: | Benzeneethanamine,4-methoxy-3-(2-phenylethoxy)-N,N-dipropyl-, hydrochloride (9CI); NE 100 |
| CAS: | 149409-57-4 |
| Molecular Formula: | C23H33 N O2 . Cl H |
| Molecular Weight: | 0 |
| InChI: | InChI=1/C23H33NO2.ClH/c1-4-15-24(16-5-2)17-13-21-11-12-22(25-3)23(19-21)26-18-14-20-9-7-6-8-10-20;/h6-12,19H,4-5,13-18H2,1-3H3;1H |
| Molecular Structure: |
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| Properties |
| Flash Point: | 137.4°C |
| Boiling Point: | 475.2°C at 760 mmHg |
| Biological Activity: | Potent and selective σ 1 receptor antagonist (K i = 0.86 nM) that displays > 55-fold selectivity over σ 2 receptors and > 6000-fold selectivity over D 1 , D 2 , 5-HT 1A , 5-HT 2 and PCP receptors. Exhibits reversible binding (K d = 1.2 nM) and displays antipsychotic activity in vivo . Orally active. |
| Flash Point: | 137.4°C |
| Safety Data |
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