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3H-Benz[e]indole-2-carbonitrile,8-(dipropylamino)-6,7,8,9-tetrahydro-, monohydrochloride, (8R)- (9CI) (149654-41-1)

Identification
Name:3H-Benz[e]indole-2-carbonitrile,8-(dipropylamino)-6,7,8,9-tetrahydro-, monohydrochloride, (8R)- (9CI)
Synonyms:3H-Benz[e]indole-2-carbonitrile,8-(dipropylamino)-6,7,8,9-tetrahydro-, monohydrochloride, (R)-; U 92016A
CAS:149654-41-1
Molecular Formula: C19H25 N3 . Cl H
Molecular Weight: 331.888
Molecular Structure: (C19H25N3.ClH) 3H-Benz[e]indole-2-carbonitrile,8-(dipropylamino)-6,7,8,9-tetrahydro-, monohydrochloride, (R)-; U 92...
Properties
Biological Activity: Selective 5-HT 1A receptor agonist that displays high intrinsic activity (K i values are 0.4, 7.7 and 36 nM for 5-HT 1A , 5-HT 1D and D 2 receptors respectively and > 1000 nM for 5-HT 2 , D 1 , α 1 and α 2 receptors). Produces hypothermia, hypotension and 5-HT behavioral syndrome following p.o. administration.
Safety Data
 

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