Identification |
Name: | 3H-Benz[e]indole-2-carbonitrile,8-(dipropylamino)-6,7,8,9-tetrahydro-, monohydrochloride, (8R)- (9CI) |
Synonyms: | 3H-Benz[e]indole-2-carbonitrile,8-(dipropylamino)-6,7,8,9-tetrahydro-, monohydrochloride, (R)-; U 92016A |
CAS: | 149654-41-1 |
Molecular Formula: | C19H25 N3 . Cl H |
Molecular Weight: | 331.888 |
Molecular Structure: |
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Properties |
Biological Activity: | Selective 5-HT 1A receptor agonist that displays high intrinsic activity (K i values are 0.4, 7.7 and 36 nM for 5-HT 1A , 5-HT 1D and D 2 receptors respectively and > 1000 nM for 5-HT 2 , D 1 , α 1 and α 2 receptors). Produces hypothermia, hypotension and 5-HT behavioral syndrome following p.o. administration. |
Safety Data |
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