Home >> Chemicals Listing >> hot product list by P  

Propanoic acid,2,2-dimethyl-,4-[[[2-[[(carboxymethyl)amino]carbonyl]phenyl]amino]sulfonyl]phenyl ester,sodium salt (1:1) (150374-95-1)

Identification
Name:Propanoic acid,2,2-dimethyl-,4-[[[2-[[(carboxymethyl)amino]carbonyl]phenyl]amino]sulfonyl]phenyl ester,sodium salt (1:1)
Synonyms:Glycine,N-[2-[[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-,monosodium salt (9CI);ONO 5046-Na;Sivelestat sodium;Sodium sivelestat;
CAS:150374-95-1
Molecular Formula: C20H21N2NaO7S
Molecular Weight: 456.44
InChI: InChI=1/C20H22N2O7S.Na/c1-20(2,3)19(26)29-13-8-10-14(11-9-13)30(27,28)22-16-7-5-4-6-15(16)18(25)21-12-17(23)24;/h4-11,22H,12H2,1-3H3,(H,21,25)(H,23,24);/q;+1/p-1
Molecular Structure: (C20H21N2NaO7S) Glycine,N-[2-[[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-,monosodium salt (9CI);O...
Properties
Flash Point: °C
Boiling Point: °Cat760mmHg
Density:g/cm3
Biological Activity: Selective leukocyte elastase inhibitor (IC 50 = 44 nM) that displays no activity at a range of other proteases. Inhibits NF- κ B activation and LTB 4 -induced neutrophil transmigration in vitro . Significantly attenuates ischemia-induced spinal cord injury, decreases serum cytokine levels and reduces acute inflammatory lung injury in vivo .
Flash Point: °C
Safety Data
 

Other Product