| Identification | |
| Name: | Benzenesulfonamide,4-methyl-N-(phenylmethyl)- |
| Synonyms: | p-Toluenesulfonamide,N-benzyl- (6CI,7CI,8CI); 4-methyl-N-(phenylmethyl)benzenesulfonamide;Benzyl(4-toluenesulfonyl)amine; N-Benzyl-4-methylbenzenesulfonamide;N-Benzyl-p-toluenesulfonamide; N-Benzyl-p-tosylamide; N-Tosylbenzylamine; NSC37123 |
| CAS: | 1576-37-0 |
| Molecular Formula: | C14H15 N O2 S |
| Molecular Weight: | 261.3394 |
| InChI: | InChI=1S/C14H15NO2S/c1-12-7-9-14(10-8-12)18(16,17)15-11-13-5-3-2-4-6-13/h2-10,15H,11H2,1H3 |
| Molecular Structure: |  |
| Properties | |
| Melting Point: | 116 - 118 ºC |
| Flash Point: | 207.3ºC |
| Boiling Point: | 419.1 ºC at 760 mmHg |
| Density: | 1.204 g/cm3 |
| Refractive index: | 1.589 |
| Water Solubility: | Soluble to 100 mM in DMSO or to 70 mM in ethanol |
| Solubility: | Soluble to 100 mM in DMSO or to 70 mM in ethanol |
| Appearance: | White crystalline solid |
| Specification: | White Solid usageEng:A potent inhibitor of skeletal muscle Ca2+-stimulated myosin S1 ATPase (IC50 approx. 5uM) activity. Reversible blocks the gliding motility. Also weakens myosin interaction with F-actin. Does not affect platelet myosin II |
| Biological Activity: | Selective inhibitor of the ATPase activity of skeletal muscle myosin II subfragment 1 (S1) (IC 50 ~ 5 mM). Reversibly blocks gliding motility and suppresses force and twitch production in fast skeletal muscle. |
| Flash Point: | 207.3ºC |
| Storage Temperature: | Desiccate at RT |
| Usage: | A potent inhibitor of skeletal muscle Ca2+-stimulated myosin S1 ATPase (IC50 approx. 5uM) activity. Reversible blocks the gliding motility. Also weakens myosin interaction with F-actin. Does not affect platelet myosin II |
| Safety Data | |
 |
|
