Home >> Chemicals Listing >> hot product list by I  

Indinavir sulfate (157810-81-6)

Identification
Name:Indinavir sulfate
Synonyms:(alphaR,gammaS,2S)-alpha-Benzyl-2-(tert-butylcarbamoyl)-gamma-hydroxy-N-((1S,2R)-2-hydroxy-1-indanyl)-4-(3-pyridylmethyl)-1-piperazinevaleramide sulfate (1:1) (salt);D-erythro-Pentonamide,2,3,5-trideoxy-N-[(1S,- 2R)-2,3-dihydro-2-hydroxy-1H-inden-1- yl]-5-[(2S)-2-[[(1,1-dimethylethyl)amino]- carbonyl]-4-(3-pyridinylmethyl)-1- piperazinyl]-2-(phenylmethyl)-,sulfate (1:1) (salt);Indinavir Sulfate(Anti-AIDS);MK639;
CAS:157810-81-6
EINECS: 207-586-9
Molecular Formula: C36H47N5O4.H2SO4
Molecular Weight: 711.96
InChI: InChI=1/C36H47N5O4.H2O4S/c1-36(2,3)39-35(45)31-24-40(22-26-12-9-15-37-21-26)16-17-41(31)23-29(42)19-28(18-25-10-5-4-6-11-25)34(44)38-33-30-14-8-7-13-27(30)20-32(33)43;1-5(2,3)4/h4-15,21,28-29,31-33,42-43H,16-20,22-24H2,1-3H3,(H,38,44)(H,39,45);(H2,1,2,3,4)/t28-,29+,31+,32-,33+;/m1./s1
Molecular Structure: (C36H47N5O4.H2SO4) (alphaR,gammaS,2S)-alpha-Benzyl-2-(tert-butylcarbamoyl)-gamma-hydroxy-N-((1S,2R)-2-hydroxy-1-indanyl...
Properties
Melting Point: 150-153
Density:g/cm3
Solubility:<0.1 g/100 mL in water
Appearance:White powder
Usage:

  Indinavir sulfate (157810-81-6) is a member of the novel hydroxyaminopentane amide class of HIV-1 protease inhibitors. AntiviralPatients with antiretroviral agents (such as: nucleoside and non-nucleoside reverse transcriptase inhibitor) combination therapy of HIV-I infection in adults.It alone is inappropriate to the clinical treatment of nucleoside or non-nucleoside reverse transcriptase inhibitor treatment of adult patients.

Safety Data
Hazard Symbols