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Benzo[1,2-b:4,5-b']dipyrrole-1(2H)-carboxamide,3,5-dihydro-5-methyl-N-3-pyridinyl- (158942-04-2)

Identification
Name:Benzo[1,2-b:4,5-b']dipyrrole-1(2H)-carboxamide,3,5-dihydro-5-methyl-N-3-pyridinyl-
Synonyms:SB 206553;5-Methyl-N-(pyridin-3-yl)-3,5-dihydropyrrolo[2,3-f]indole-1(2H)-carboxamide;5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-carboxylic acid pyridin-3-ylamide;Pyrrolo[2,3-f]indole-1(2H)-carboxamide, 3,5-dihydro-5-methyl-N-3-pyridinyl-;
CAS:158942-04-2
Molecular Formula: C17H16N4O
Molecular Weight: 292.34
InChI: InChI=1/C17H16N4O.ClH/c1-20-7-4-12-10-16-13(9-15(12)20)5-8-21(16)17(22)19-14-3-2-6-18-11-14;/h2-4,6-7,9-11H,5,8H2,1H3,(H,19,22);1H
Molecular Structure: (C17H16N4O) SB 206553;5-Methyl-N-(pyridin-3-yl)-3,5-dihydropyrrolo[2,3-f]indole-1(2H)-carboxamide;5-Methyl-3,5-d...
Properties
Melting Point: 250 - 252 ºC
Density:1.33 g/cm3
Water Solubility:H2O: 30 mg/mL
Solubility:H2O: 30 mg/mL
Appearance:Yellow solid
Biological Activity: Potent and selective 5-HT 2B /5-HT 2C receptor antagonist (rat 5-HT 2B pA 2 = 8.89, human 5-HT 2C pK i = 7.92). Displays > 80-fold selectivity over all other 5-HT receptor subtypes and a variety of other receptors (pK i < 6). Centrally active following oral administration in vivo .
Color: brown
Safety Data
 

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