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Rapamycin,42-O-(2-hydroxyethyl)- (159351-69-6)

Identification
Name:Rapamycin,42-O-(2-hydroxyethyl)-
Synonyms:40-O-(2-Hydroxyethyl)rapamycin;42-O-(2-Hydroxy)ethylrapamycin;Certican;RAD;RAD 001;SDZ-RAD;XIENCE V;
CAS:159351-69-6
Molecular Formula: C53H83NO14
Molecular Weight: 958.22442
InChI: InChI=1S/C53H83NO14/c1-32-16-12-11-13-17-33(2)44(63-8)30-40-21-19-38(7)53(62,68-40)50(59)51(60)54-23-15-14-18-41(54)52(61)67-45(35(4)28-39-20-22-43(66-25-24-55)46(29-39)64-9)31-42(56)34(3)27-37(6)48(58)49(65-10)47(57)36(5)26-32/h11-13,16-17,27,32,34-36,38-41,43-46,48-49,55,58,62H,14-15,18-26,28-31H2,1-10H3/b13-11+,16-12+,33-17+,37-27+/t32-,34-,35-,36-,38-,39+,40+,41+,43-,44+,45+,46-,48-,49+,53-/m1/s1
Molecular Structure: (C53H83NO14) 40-O-(2-Hydroxyethyl)rapamycin;42-O-(2-Hydroxy)ethylrapamycin;Certican;RAD;RAD 001;SDZ-RAD;XIENCE V;
Properties
Density:1.18 g/cm3
Refractive index:1.548
Water Solubility:Soluble in DMSO and ethanol, up to about 25 mg/mL
Solubility:Soluble in DMSO and ethanol, up to about 25 mg/mL
Appearance:Off-white to light yellow powd
Usage:

Macrolide immunosuppressant; derivative of Rapamycin. Inhibits cytokine-mediated lymphocyte proliferation

Safety Data