| Identification |
| Name: | 1,2,3-Oxadiazolium,5-amino-3-(4-morpholinyl)-, chloride (1:1) |
| Synonyms: | 3-Morpholinosydnoniminehydrochloride;Linsidomine chlorhydrate;Linsidomine hydrochloride;1,2,3-Oxadiazolium,5-amino-3-(4-morpholinyl)-, chloride (9CI);Sydnone imine, 3-(4-morpholinyl)-,monohydrochloride;Sydnone imine, 3-morpholino-, monohydrochloride (8CI);3-Morpholinosydnone imine monohydrochloride; |
| CAS: | 16142-27-1 |
| EINECS: | 247-207-4 |
| Molecular Formula: | C6H11N4O2.Cl |
| Molecular Weight: | 206.66 |
| InChI: | InChI=1/C6H11N4O2.ClH/c7-6-5-10(8-12-6)9-1-3-11-4-2-9;/h5H,1-4,7H2;1H/q+1;/p-1 |
| Molecular Structure: |
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| Properties |
| Melting Point: | 186 ºC |
| Stability: | No data. |
| Water Solubility: | soluble |
| Solubility: | soluble in water |
| Appearance: | white needles or slightly yellowish white crystalline powder |
| Biological Activity: | This compound (the active product of the prodrug SIN-10, molsidomine) acts as a vasodilator and inhibitor of platelet aggregation; longer acting than nitroprusside or nitroglycerin. Decreases myocardial necrosis and reperfusion-induced endothelial dysfunction in models of myocardial ischemia-reperfusion. |
| Storage Temperature: | -20°C |
| Usage: | SIN-1 is a metabolite of the vasodilator molsidomine and is considered to be a peroxynitrite releasing compound |
| Safety Data |
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