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1,2,3-Oxadiazolium,5-amino-3-(4-morpholinyl)-, chloride (1:1) (16142-27-1)

Identification
Name:1,2,3-Oxadiazolium,5-amino-3-(4-morpholinyl)-, chloride (1:1)
Synonyms:3-Morpholinosydnoniminehydrochloride;Linsidomine chlorhydrate;Linsidomine hydrochloride;1,2,3-Oxadiazolium,5-amino-3-(4-morpholinyl)-, chloride (9CI);Sydnone imine, 3-(4-morpholinyl)-,monohydrochloride;Sydnone imine, 3-morpholino-, monohydrochloride (8CI);3-Morpholinosydnone imine monohydrochloride;
CAS:16142-27-1
EINECS: 247-207-4
Molecular Formula: C6H11N4O2.Cl
Molecular Weight: 206.66
InChI: InChI=1/C6H11N4O2.ClH/c7-6-5-10(8-12-6)9-1-3-11-4-2-9;/h5H,1-4,7H2;1H/q+1;/p-1
Molecular Structure: (C6H11N4O2.Cl) 3-Morpholinosydnoniminehydrochloride;Linsidomine chlorhydrate;Linsidomine hydrochloride;1,2,3-Oxadia...
Properties
Melting Point: 186 ºC
Stability:No data.
Water Solubility:soluble
Solubility:soluble in water
Appearance:white needles or slightly yellowish white crystalline powder
Biological Activity: This compound (the active product of the prodrug SIN-10, molsidomine) acts as a vasodilator and inhibitor of platelet aggregation; longer acting than nitroprusside or nitroglycerin. Decreases myocardial necrosis and reperfusion-induced endothelial dysfunction in models of myocardial ischemia-reperfusion.
Storage Temperature: -20°C
Usage:SIN-1 is a metabolite of the vasodilator molsidomine and is considered to be a peroxynitrite releasing compound
Safety Data
 

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