| Identification |
| Name: | 1H-Pyrazole,5-(4-fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-3-(trifluoromethyl)- |
| Synonyms: | SC 58125 |
| CAS: | 162054-19-5 |
| Molecular Formula: | C17H12 F4 N2 O2 S |
| Molecular Weight: | 384.35 |
| InChI: | InChI=1/C17H12F4N2O2S/c1-26(24,25)14-8-6-13(7-9-14)23-15(10-16(22-23)17(19,20)21)11-2-4-12(18)5-3-11/h2-10H,1H3 |
| Molecular Structure: |
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| Properties |
| Flash Point: | 263.8°C |
| Boiling Point: | 512.6°Cat760mmHg |
| Density: | 1.41g/cm3 |
| Refractive index: | 1.573 |
| Biological Activity: | Selective cyclooxygenase 2 (COX-2) inhibitor (IC 50 values are 0.04 and >100 μ M for COX-2 and COX-1 respectively). Anti-inflammatory; blocks edema and hyperalgesia in vivo following an inflammatory insult, without causing gastric mucosal damage. Also displays antitumor activity. |
| Flash Point: | 263.8°C |
| Safety Data |
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