Identification |
Name: | Ethanesulfonamide,N-[(3R,4S)-6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methyl- |
Synonyms: | (-)-Chromanol 293B;Ethanesulfonamide,N-(6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl)-N-methyl-,trans-(-)-; |
CAS: | 163163-24-4 |
Molecular Formula: | C15H20N2O4S |
Molecular Weight: | 324.4 |
Molecular Structure: |
![(C15H20N2O4S) (-)-Chromanol 293B;Ethanesulfonamide,N-(6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4...](https://img1.guidechem.com/chem/e/dict/109/163163-24-4.jpg) |
Properties |
Flash Point: | 240.6°C |
Boiling Point: | 474.1°Cat760mmHg |
Density: | 1.33g/cm3 |
Solubility: | DMSO: 18 mg/mL |
Appearance: | White solid |
Biological Activity: | Enantiomer that selectively inhibits the slow component of delayed rectifier K + current (I Ks ). Block is use-dependent and 7-fold more potent than the (+)-(3S,4R) enantiomer (IC 50 values are 1.36 and 9.6 μ M respectively). Has negligible inhibitory action at hERG channels (IC 50 > 30 μ M). |
Flash Point: | 240.6°C |
Storage Temperature: | −20°C |
Color: | white |
Safety Data |
Hazard Symbols |
Xn: Harmful
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