| Identification | |
| Name: | Acetamide,N-[[(5S)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]- |
| Synonyms: | Acetamide,N-[[3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-, (S)-;(S)-Linezolid;Linospan;Linox;N-[[(5S)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide;PNU 100766;U 100766;Zyvox; |
| CAS: | 165800-03-3 |
| Molecular Formula: | C16H20FN3O4 |
| Molecular Weight: | 337.35 |
| InChI: | InChI=1/C16H20FN3O4/c1-11(21)18-9-13-10-20(16(22)24-13)12-2-3-15(14(17)8-12)19-4-6-23-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m1/s1 |
| Molecular Structure: | ![(C16H20FN3O4) Acetamide,N-[[3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-, (S)-;(S)-Linezolid...](https://img.guidechem.com/casimg/165800-03-3.gif) |
| Properties | |
| Melting Point: | 176-178oC |
| Flash Point: | 307.9 oC |
| Boiling Point: | 585.5 oC at 760 mmHg |
| Density: | 1.302 g/cm3 |
| Refractive index: | 1.553 |
| Solubility: | Insoluble |
| Appearance: | White Solid |
| Specification: |
? Acetamide,N-[[(5S)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]- (CAS NO.165800-03-3), its Synonyms are Linezolid ; N-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide ; Zivoxid ; Zyvox ; Acetamide, N-((3-(3-fluoro-4-(4-morpholinyl)phenyl)-2-oxo-5-oxazolidinyl)methyl)-, (S)- . |
| Biological Activity: | Oxazolidinone antibiotic. Inhibits bacterial protein synthesis prior to chain initiation. Displays potent antibacterial activity against a variety of multidrug-resistant gram-positive microbes in vitro and in vivo . |
| Flash Point: | 307.9 oC |
| Storage Temperature: | Store in original container in a cool dark place. |
| Color: | White crystals from ethyl acetate and hexanes |
| Usage: | Prototype of the oxazolidinone antimicrobials; inhibits bacterial mRNA translation. |
| Safety Data | |
| Hazard Symbols |
Xn: Harmful
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